Howard G Shertzer: search on Z-Library

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1

Benzo[a]pyrene-Induced Toxicity: Paradoxical Protection in Cyp1a1(−/−) Knockout Mice Having Increased Hepatic BaP–DNA Adduct Levels

Shigeyuki Uno, Timothy P. Dalton, Howard G. Shertzer, Mary Beth Genter, David Warshawsky, Glenn Talaska, Daniel W. Nebert

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 143 KB

english, 2001

2

REGULATION OF GENE EXPRESSION BY REACTIVE OXYGEN

Dalton, Timothy P., Shertzer, Howard G., Puga, Alvaro

Journal:

Annual Review of Pharmacology

Year:

1999

Language:

english

File:

PDF, 248 KB

english, 1999

3

Over-the-counter analgesics normalize blood glucose and body composition in mice fed a high fat diet

Eric L. Kendig, Scott N. Schneider, Deborah J. Clegg, Mary Beth Genter, Howard G. Shertzer

Journal:

Biochemical Pharmacology

Year:

2008

Language:

english

File:

PDF, 306 KB

english, 2008

4

Anaerobic rat heart: Mitochondrial role in calcium uptake and contractility

Howard G. Shertzer, Joseph Cascarano

Journal:

Journal of Experimental Zoology Part A Ecological Genetics and Physiology

Year:

1979

Language:

english

File:

PDF, 947 KB

english, 1979

5

Balancer-Cre transgenic mouse germ cells direct the incomplete resolution of a tri-loxP-targeted Cyp1a1 allele, producing a conditional knockout allele

Shigeyuki Uno, Bin Wang, Howard G Shertzer, Daniel W Nebert, Timothy P Dalton

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 165 KB

english, 2003

6

Inhibition of alveolar macrophage killing by di(2-ethylhexyl)phthalate

Howard G. Shertzer, Marcell B. Bally, Dennis J. Opheim

Journal:

Archives of Environmental Contamination and Toxicology

Year:

1985

Language:

english

File:

PDF, 375 KB

english, 1985

7

Activation of transcription factors activator protein-1 and nuclear factor-κB by 2,3,7,8-Tetrachlorodibenzo-p-dioxin

Alvaro Puga, Sonya J Barnes, Ching-yi Chang, Huan Zhu, Kenneth P Nephew, Sohaib A Khan, Howard G Shertzer

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 533 KB

english, 2000

8

Induction of cellular oxidative stress by aryl hydrocarbon receptor activation

Timothy P Dalton, Alvaro Puga, Howard G Shertzer

Journal:

Chemico-Biological Interactions

Year:

2002

Language:

english

File:

PDF, 134 KB

english, 2002

9

Enzyme Induction by L-Buthionine(S,R)-Sulfoximine in Cultured Mouse Hepatoma Cells

Shertzer, Howard G., Vasiliou, Vasilis, Liu, Rui-Ming, Tabor, M. Wilson, Nebert, Daniel W.

Journal:

Chemical Research in Toxicology

Year:

1995

Language:

english

File:

PDF, 1.29 MB

english, 1995

10

High glucose concentration in isotonic media alters Caco-2 cell permeability

Vanessa M. D Souza, Howard G. Shertzer, Anil G. Menon, Giovanni M. Pauletti

Journal:

The AAPS Journal

Year:

2003

Language:

english

File:

PDF, 158 KB

english, 2003

11

Tetrahydroindenoindole inhibits the progression of diabetes in mice

Howard G. Shertzer, Scott N. Schneider, Eric L. Kendig, Deborah J. Clegg, David A. D’Alessio, Elisabet Johansson, Mary Beth Genter

Journal:

Chemico-Biological Interactions

Year:

2009

Language:

english

File:

PDF, 332 KB

english, 2009

12

Comparison of mouse hepatic mitochondrial versus microsomal cytochromes P450 following TCDD treatment

Mary Beth Genter, Corey D. Clay, Timothy P. Dalton, Hongbin Dong, Daniel W. Nebert, Howard G. Shertzer

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 221 KB

english, 2006

13

Glutathione deficient C57BL/6J mice are not sensitized to ozone-induced lung injury

Elisabet Johansson, Scott C. Wesselkamper, Howard G. Shertzer, George D. Leikauf, Timothy P. Dalton, Ying Chen

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 352 KB

english, 2010

14

Benzo(a)pyrene Metabolism in the Isolated Perfused Mouse Lung

Skelly, Michael F., Shertzer, Howard G.

Journal:

Experimental Lung Research

Year:

1983

Language:

english

File:

PDF, 662 KB

english, 1983

15

Toward the evaluation of function in genetic variability: Characterizing human SNP frequencies and establishing BAC-transgenic mice carrying the human CYP1A1_CYP1A2 locus

Zhengwen Jiang, Timothy P. Dalton, Li Jin, Bin Wang, Yutaka Tsuneoka, Howard G. Shertzer, Ranjan Deka, Daniel W. Nebert

Journal:

Year:

2005

Language:

english

File:

PDF, 338 KB

english, 2005

16

New antioxidants incorporating indole and indoline chromophores

David W Brown, Paul R Graupner, Malcolm Sainsbury, Howard G Shertzer

Journal:

Year:

1991

Language:

english

File:

PDF, 1.62 MB

english, 1991

17

Glutamate–cysteine ligase modifier subunit: mouse Gclm gene structure and regulation by agents that cause oxidative stress

Willy A. Solis, Timothy P. Dalton, Matthew Z. Dieter, Sarah Freshwater, Judy M. Harrer, Lei He, Howard G. Shertzer, Daniel W. Nebert

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 644 KB

english, 2002

18

Ozone-induced acute lung injury: genetic analysis of F 2 mice generated from A/J and C57BL/6J strains

Prows, Daniel R., Daly, Mark J., Shertzer, Howard G., Leikauf, George D.

Journal:

American journal of physiology. Lung cellular and molecular physiology

Year:

1999

Language:

english

File:

PDF, 350 KB

english, 1999

19

Indole-3-carbinol and indole-3-acetonitrile influence on hepatic microsomal metabolism

Howard G. Shertzer

Journal:

Toxicology and Applied Pharmacology

Year:

1982

Language:

english

File:

PDF, 822 KB

english, 1982

20

TCDD decreases ATP levels and increases reactive oxygen production through changes in mitochondrial F0F1-ATP synthase and ubiquinone

Howard G. Shertzer, Mary Beth Genter, Dongxiao Shen, Daniel W. Nebert, Ying Chen, Timothy P. Dalton

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 547 KB

english, 2006

21

Glutathione Redox State Regulates Mitochondrial Reactive Oxygen Production

Shen, Dongxiao, Dalton, Timothy P., Nebert, Daniel W., Shertzer, Howard G.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 282 KB

english, 2005

22

Early onset senescence occurs when fibroblasts lack the glutamate–cysteine ligase modifier subunit

Ying Chen, Elisabet Johansson, Yunxia Fan, Howard G. Shertzer, Vasilis Vasiliou, Daniel W. Nebert, Timothy P. Dalton

Journal:

Free Radical Biology and Medicine

Year:

2009

Language:

english

File:

PDF, 1.23 MB

english, 2009

23

Letter to the editor

Howard G Shertzer, Timothy P Dalton, Glenn Talaska, Daniel W Nebert

Journal:

Toxicology and Applied Pharmacology

Year:

2003

Language:

english

File:

PDF, 44 KB

english, 2003

24

Characterization of novel indenoindoles. Part I. Structure-activity relationships in different model systems of lipid peroxidation

Christer Westerlund, Ann-Margret Östlund-Lindqvist, Malcolm Sainsbury, Howard G. Shertzer, Per-Ove Sjöquist

Journal:

Biochemical Pharmacology

Year:

1996

Language:

english

File:

PDF, 702 KB

english, 1996

25

Effects of ClO 2 on the Absorption and Distribution of Dietary Iodide in the Rat

HARRINGTON, ROBERT M., SHERTZER, HOWARD G., BERCZ, J. PETER

Journal:

Toxicological Sciences

Year:

1985

Language:

english

File:

PDF, 497 KB

english, 1985

26

Indole-3-carbinol protects against covalent binding of benzo[a]pyrene and N-nitrosodimethylamine metabolites to mouse liver macromolecules

Howard G. Shertzer

Journal:

Chemico-Biological Interactions

Year:

1984

File:

PDF, 540 KB

1984

27

Dioxin Causes a Sustained Oxidative Stress Response in the Mouse

Howard G. Shertzer, Daniel W. Nebert, Alvaro Puga, Michelle Ary, David Sonntag, Kathleen Dixon, Lindsey J. Robinson, Eli Cianciolo, Timothy P. Dalton

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 87 KB

english, 1998

28

SPECTROPHOTOMETRIC ASSAY FOR ACETANILIDE 4-HYDROXYLASE, AN ESTIMATE OF CYP1A2 ENZYME ACTIVITY

G. Shertzer, Daniel W. Nebert, Albe, Howard

Journal:

Toxicology Mechanisms and Methods

Year:

2001

Language:

english

File:

PDF, 203 KB

english, 2001

29

Peroxide removal from organic solvents and vegetable oils

Shertzer, Howard G., Tabor, M. Wilson

Journal:

Journal of Environmental Science and Health Part A Environmental Science and Engineering

Year:

1985

Language:

english

File:

PDF, 354 KB

english, 1985

30

Oral N-acetylcysteine rescues lethality of hepatocyte-specific Gclc-knockout mice, providing a model for hepatic cirrhosis

Ying Chen, Elisabet Johansson, Yi Yang, Marian L. Miller, Dongxiao Shen, David J. Orlicky, Howard G. Shertzer, Vasilis Vasiliou, Daniel W. Nebert, Timothy P. Dalton

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 2.61 MB

english, 2010

31

Theophylline pharmacokinetics: comparison of Cyp1a1(???/???) and Cyp1a2(???/???) knockout mice, humanized hCYP1A1_1A2 knock-in mice lacking either the mouse Cyp1a1 or Cyp1a2 gene, and Cyp1(+/+) wild-type mice

Derkenne, Sandrine, Curran, Christine P., Shertzer, Howard G., Dalton, Timothy P., Dragin, Nadine, Nebert, Daniel W.

Journal:

Pharmacogenetics and Genomics

Year:

2005

Language:

english

File:

PDF, 139 KB

english, 2005

32

Evaluation of iron binding and peroxide-mediated toxicity in rat hepatocytes

Howard G. Shertzer, Gerard L. Bannenberg, Peter Moldéus

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 772 KB

english, 1992

33

Nitrite binding to rabbit liver microsomes and effects on aminopyrine demethylation

Howard G. Shertzer, Gwen S. Duthu

Journal:

Biochemical Pharmacology

Year:

1979

Language:

english

File:

PDF, 707 KB

english, 1979

34

Hepatic mixed-function oxidase activity in mice infected with Trypanosoma brucei gambiense or treated with trypanocides

Howard G. Shertzer, James Edwin Hall, John R. Seed

Journal:

Molecular and Biochemical Parasitology

Year:

1981

Language:

english

File:

PDF, 335 KB

english, 1981

35

Retardation of benzo[a]pyrene-induced epidermal tumor formation by the potent antioxidant 4b,5,9b,10-tetrahydroindeno[1,2-b]indole

Shertzer, Howard G., Sainsbury, Malcolm, Reilman, Ray, Warshawsky, David

Journal:

Year:

1994

Language:

english

File:

PDF, 563 KB

english, 1994

36

Genetic analysis of ozone-induced acute lung injury in sensitive and resistant strains of mice

Prows, Daniel R., Shertzer, Howard G., Daly, Mark J., Sidman, Charles L., Leikauf, George D.

Journal:

Nature Genetics

Year:

1997

File:

PDF, 455 KB

1997

37

Intervention in free radical mediated hepatotoxicity and lipid peroxidation by indole-3-carbinol

Howard G. Shertzer, Marc L. Berger, M. Wilson Tabor

Journal:

Biochemical Pharmacology

Year:

1988

Language:

english

File:

PDF, 764 KB

english, 1988

38

Purification and reconstitution of the phosphate transporter from bovine heart mitochondria

Ranajit K. Banerjee, Howard G. Shertzer, Baruch I. Kanner, Efraim Racker

Journal:

Biochemical and Biophysical Research Communications

Year:

1977

Language:

english

File:

PDF, 363 KB

english, 1977

39

Glutathione-Deficient Mice Are Susceptible to TCDD-Induced Hepatocellular Toxicity but Resistant to Steatosis

Chen, Ying, Krishan, Mansi, Nebert, Daniel W., Shertzer, Howard G.

Journal:

Chemical Research in Toxicology

Year:

2012

Language:

english

File:

PDF, 2.48 MB

english, 2012

40

Stimulation of adenine nucleotide translocation in reconstituted vesicles by phosphate and the phosphate transporter

Howard G. Shertzer, Baruch I. Kanner, Ranajit K. Banerjee, Efraim Racker

Journal:

Biochemical and Biophysical Research Communications

Year:

1977

Language:

english

File:

PDF, 332 KB

english, 1977

41

The synthesis of dihydroindenoindoles

Jeremy Graham, Aleyamma Ninan, Khalid Reza, Malcolm Sainsbury, Howard G. Shertzer

Journal:

Year:

1992

Language:

english

File:

PDF, 634 KB

english, 1992

42

Dioxin exposure is an environmental risk factor for ischemic heart disease

Timothy P. Dalton, J. Kevin Kerzee, Bin Wang, Marian Miller, Mathew Z. Dieter, John N. Lorenz, Howard G. Shertzer, Daniel W. Nebert, Alvaro Puga

Journal:

Cardiovascular Toxicology

Year:

2001

Language:

english

File:

PDF, 360 KB

english, 2001

43

Hepatic microsomal alterations during chronic trypanosomiasis in the field vole, Microtus montanus

Howard G. Shertzer, James Edwin Hall, John R. Seed

Journal:

Molecular and Biochemical Parasitology

Year:

1982

Language:

english

File:

PDF, 406 KB

english, 1982

44

Relationship of membrane fluidity, chemoprotection, and the intrinsic toxicity of butylated hydroxytoluene

Howard G. Shertzer, Gerard L. Bannenberg, Mats Rundgren, Peter Moldéus

Journal:

Biochemical Pharmacology

Year:

1991

Language:

english

File:

PDF, 850 KB

english, 1991

45

Mechanisms of protection from menadione toxicity by 5,10-dihydroindeno[1,2,-b]indole in a sensitive and resistant mouse hepatocyte line

Rui-Ming Liu, Malcolm Sainsbury, M. Wilson Tabor, Howard G. Shertzer

Journal:

Biochemical Pharmacology

Year:

1993

Language:

english

File:

PDF, 993 KB

english, 1993

46

Dietary whey protein stimulates mitochondrial activity and decreases oxidative stress in mouse female brain

Shertzer, Howard G., Krishan, Mansi, Genter, Mary Beth

Journal:

Neuroscience Letters

Year:

2013

Language:

english

File:

PDF, 1.15 MB

english, 2013

47

Metalloproteinases Mediate Mucin 5AC Expression by Epidermal Growth Factor Receptor Activation

Deshmukh, Hitesh S., Case, Lisa M., Wesselkamper, Scott C., Borchers, Michael T., Martin, Linda D., Shertzer, Howard G., Nadel, Jay A., Leikauf, George D.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2005

Language:

english

File:

PDF, 328 KB

english, 2005

48

Dioxin Increases Reactive Oxygen Production in Mouse Liver Mitochondria

Albert P. Senft, Timothy P. Dalton, Daniel W. Nebert, Mary Beth Genter, Richard J. Hutchinson, Howard G. Shertzer

Journal:

Toxicology and Applied Pharmacology

Year:

2002

Language:

english

File:

PDF, 124 KB

english, 2002

49

Differences in Pulmonary Metabolism of Benzo(a)pyrene in Inbred Mouse Strains, Using the Isolated Perfused Lung

Skelly, Michael F., Shertzer, Howard G.

Journal:

Acta Pharmacologica et Toxicologica

Year:

1985

Language:

english

File:

PDF, 6.51 MB

english, 1985

50

Rapid analysis of DNA strand breaks in soft tissues

Stanton R. Morris, Howard G. Shertzer

Journal:

Environmental and Molecular Mutagenesis

Year:

1985

Language:

english

File:

PDF, 605 KB

english, 1985

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